diff --git a/README.md b/README.md
index bef0e99..4f24163 100644
--- a/README.md
+++ b/README.md
@@ -19,7 +19,7 @@ The code in this repository is named _PROPKA 3_ and it is based on the original
 
 ## Requirements
 
-PROPKA 3 requires Python 3.5 or higher.  Additional requirements are specified in the `requirements.txt` file and automatically satisfied when installing with [pip](https://pip.pypa.io).
+PROPKA 3 requires Python 3.6 or higher.  Additional requirements are specified in the `requirements.txt` file and automatically satisfied when installing with [pip](https://pip.pypa.io).
 
 ## Installation
 
diff --git a/setup.py b/setup.py
index 44f6a56..9efaf41 100755
--- a/setup.py
+++ b/setup.py
@@ -45,7 +45,6 @@ See http://propka.org/ for the PROPKA web server.
         'Operating System :: MacOS :: MacOS X',
         'Operating System :: Microsoft :: Windows',
         'Programming Language :: Python',
-        'Programming Language :: Python :: 3.5',
         'Programming Language :: Python :: 3.6',
         'Programming Language :: Python :: 3.7',
         'Programming Language :: Python :: 3.8',
@@ -56,7 +55,7 @@ See http://propka.org/ for the PROPKA web server.
     package_data={'propka': ['*.dat', '*.cfg', '*.json']},
     entry_points={'console_scripts': ['propka3 = propka.run:main', ]},
     zip_safe=True,
-    python_requires='>=3.5',
+    python_requires='>=3.6',
     tests_require=["pandas", "numpy", "pytest"],
     test_suite="tests",
     )